A Human Angle

Among the learning features in the book are our "Human Angle" boxes, which put the material covered in text into the context of human health and disease. Below you can explore some of these boxes for yourself. 

We'll be adding new examples over the coming months. To get the latest sample content, bookmark our site, or sign up for updates.  



Yersina pestis is a bacterial species that causes a deadly disease known as the Plague. Currently, outbreaks of the Plague occur in very few parts of the world, but ancient outbreaks had a major role... 

[Read more]

 

Mutations that arise spontaneously usually occur as a result of unrepaired errors during replication, as discussed in Chapter 4, or as transposable element movement, as discussed in Chapter 3.  However, a few mutant alleles arise...

[Read more]

 

ABO Blood Types

Among genetic traits that we all share, the most familiar single gene trait in humans is probably our ABO blood type.  Other familiar shared heritable human traits, such eye color, are not controlled by a single gene...

[Read more]

 

How Toadstools Affect Transcription

One of the most common and widespread mushrooms in Europe is also among the most toxic toadstools.  Amanita phalloides (familiarly known as the death cap mushroom or toadstool) grows throughout European forests...

[Read more]

 

The Sickle Cell Trait Heterozygote Advantage

According to eastern Nigerian mythology, an Ogbanje is a child who dies within a few months or years of birth and returns to a mythical land, only to re-enter the womb of his or her mother and be born again...

[Read more]

 

X Chromosome Inactivation and Xist

Dosage compensation in mammals occurs by the inactivation of one of the two X chromosomes in females; the inactive X chromosome is condensed into heterochromatin as a cytologically recognizable Barr body or sex chromatin body...

[Read more]